·1 platform·Arcade
Co-op support
1 of 6 modesS.E.M.I.: Side Effects May Include... has online co-op for up to 4 players on PC. There is no split-screen on any platform.
Online Co-op
Up to 4 players
| Platform | Online | Couch | Split-screen | LAN | Drop-in | Campaign | Online max | Local max |
|---|---|---|---|---|---|---|---|---|
 | 4 | – |
supportednot supportedVerified against Steam store categories and Co-Optimus
Not supported/Local Co-op · Split-screen · LAN Play · Drop-in / Drop-out · Campaign Co-op
About
Developed by Two Horn Unicorn, S.E.M.I.: Side Effects May Include... is an arcade / hack and slash/beat 'em up / indie game released on Oct 31, 2025.
Screenshots
Details
ReleasedOct 31, 2025
DeveloperTwo Horn Unicorn
PublisherTwo Horn Unicorn
Age ratingE10+
Players1–4
Steam reviews86% of 112 · Very Positive
Available on
PC1 of 6
Tags
ActionComedyPartyAction CombatAction PlatformerAction RoguelikeCrazyEscape GameFunnyLogic PuzzleOnline CoopPhysicsPhysics PuzzlesPuzzle PlatformerRagdoll Physics
